Fungal infection attack Lungs in Covid patients

By: Dushyant Singh Thakur

Aspergillus latus, a species of fungus previously found only in soil or plants, has been found for the first time in a hospital environment by an international group of researchers.

The group sequenced its genome and discovered that it is actually a hybrid and is up to three times more drug-resistant than the two species from which it derives.

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Aspergillosis is a lung disease caused by fungi of this genus, especially A.fumigatus,which is widely found in plants and soil.

“In about 90 per cent of cases,infection by Aspergillus is caused by A.fumigatus,but in some human genetic diseases,A.Nidulans is a more frequent cause.

“To our surprise, six out 10 samples contained a fungus that had never before been found to infect people,”said Goldman.

Currently have four strains that were isolated from patients who died of COVID-19 in Europe and will sequence their genomes to identify the species and see if they’re favoured by the disease,a informed Goldman.

Fungal infections in the lungs can be more serious and often cause symptoms that are similar to other illnesses,such as the flu or tuberculosis.Fungal meningitis and bloodstream infections are less common than skin and lung infections but can be life-threatening.

History findings in persons with fungal pneumonia may include the following:
Fever.

Cough,usually nonproductive.
Pleuritic chest pain or dull discomfort.
Progressive dyspnea leading to respiratory failure.
Airway obstructive symptoms from enlarged mediastinal adenopathy in the endemic mycoses.
Pulmonary disease occurs when the fungus is inhaled and phagocytized by neutrophils and macrophages in the alveoli. Itraconazole is used as monotherapy for mild and chronic pulmonary disease. Amphotericin B (AmB) with itraconazole is recommended for moderate-to-severe histoplasmosis.
Foods to be avoided—
Common culprits include:
Cheese.
Mushrooms.
Vinegar and foods containing vinegar, such as salad dressing, Ketchups, and pickles.
Sour cream, sour milk, and buttermilk.
Meat or fish.
Breads and other food made with yeast.
Jarred jams and jellies.
recent increase in the use of immunosuppressants to treat human illnesses, it is estimated that A. fumigatus may be responsible for over 600,000 deaths annually with a mortality rate between 25-90%.

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